HCID 67021600, compound → Methyl 4-amino-2,6-dichlorobenzeneacetate

Participants

Reaction Steps

A suspension of (2,6-dichloro-4-nitro-phenyl)-acetic acid methyl ester (12.7 g, 47.13 mmol) and Raney Nickel (3 g) in MeOH (500 mL) is stirred for 3.5 h at rt, under a hydrogen atmosphere. The reaction mixture is filtered through a pad of celite and concentrated to afford the title compound as a yellow solid: ESI-MS: 232.0/234.0 [M-H]−; tR=3.11 min (System 2).

Provenance & Evidence