Ethyl orthoformate → HCID 67021389, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of [4-(3-amino-pyridin-2-ylamino)-2-methyl-phenyl]-acetic acid methyl ester (1.92 g, 7.08 mmol) and triethyl orthoformate (30 mL, 181 mmol, 26 equiv) is stirred for 3 h at 150° C. The resulting mixture is allowed to cool to rt and concentrated in vacuo to provide the title compound: ES-MS: 282.1 [M+H]+; tR=3.39 min (System 1).

Provenance & Evidence