HCID 86609594, compound → HCID 66858583, compound

Participants

Reaction Steps

A solution of 4-(3-Benzyloxy-2-methoxy-17-oxo-estra-1,3,5(10)-trien-15β-yl)-but-2-enoic acid methyl ester (17.3 g, 2.36 mmol) in THF (440 ml) and MeOH (440 ml) was purged with H2 (balloon). Then Pd (10% on carbon, 50% H2O) (1.80 g) was added, and the mixture obtained was stirred under H2 pressure for over night. The reaction mixture was filtered over two filter papers and concentrated in vacuo to yield the desired compound (VIIβ-(C2-B)-3a-1) (13.8 g, 97%), which represents a compound falling under the scope of the present invention.

Provenance & Evidence