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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1661221Generated: October 26, 2026

2-Bromo-4-methylpyridine → [1-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-(4-methyl-pyridin-2-yl)-methanone

https://huagongshe.com/reaction/1661221

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-4-methylpyridineHCID 2734087—
Reactant1-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazole-4-carboxylic acid methoxy-methyl-amideHCID 86634428—
Product[1-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-(4-methyl-pyridin-2-yl)-methanoneHCID 16678808—

Reaction Steps

This compound was prepared by method C using compound 12b and 2-bromo-4-methylpyridine. HRMS (ESI+): m/z=388.1481 [M+H]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030339B2
Source datasetuspto-grants-2011_10
ORD IDord-d75cdc5223f54139bf35876665fe4434
Source noteuspto-grants-2011_10