1-(Ethoxymethyl)-1H-imidazole → (1-Ethoxymethyl-1H-imidazol-2-yl)-[1-(5'-fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-methanone
Reaction equation
CON(C)[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:12]=[C:13]([C:17]3[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:18]=3[O:24][CH3:25])[CH:14]=[CH:15][CH:16]=2)[CH:10]=1)=[O:5].[CH2:27]([O:29][CH2:30][N:31]1[CH:35]=[CH:34][N:33]=[CH:32]1)[CH3:28]>>[CH2:27]([O:29][CH2:30][N:31]1[CH:35]=[CH:34][N:33]=[C:32]1[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:12]=[C:13]([C:17]3[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:18]=3[O:24][CH3:25])[CH:14]=[CH:15][CH:16]=2)[CH:10]=1)=[O:5])[CH3:28]Participants
3
Procedure
This compound is prepared by method C using compound 12b and 1-(ethoxymethyl)imidazole.
Workup
- customThis compound is prepared by method C
Sources & evidence
- ORD record
- ord-eb1dab404b714927b8394210229a13d1
- Source dataset
- uspto-grants-2011_10
- Patent number
- US08030339B2
Reaction notes
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