1-Methylimidazole → (1-Methyl-1H-Imidazol-2-yl)-[1-(2'-trifluoromethoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-methanone
Reaction equation
CON(C)[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:12]=[C:13]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[O:23][C:24]([F:27])([F:26])[F:25])[CH:14]=[CH:15][CH:16]=2)[CH:10]=1)=[O:5].[CH3:29][N:30]1[CH:34]=[CH:33][N:32]=[CH:31]1>>[CH3:29][N:30]1[CH:34]=[CH:33][N:32]=[C:31]1[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:12]=[C:13]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[O:23][C:24]([F:26])([F:25])[F:27])[CH:14]=[CH:15][CH:16]=2)[CH:10]=1)=[O:5]Participants
3
Procedure
This compound is prepared by method C using compound 12f and 1-methylimidazole
Workup
- customThis compound is prepared by method C
Sources & evidence
- ORD record
- ord-17e3bc0499474706b572ba3226ab8a28
- Source dataset
- uspto-grants-2011_10
- Patent number
- US08030339B2
Reaction notes
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