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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1661323Generated: October 30, 2026

1-Bromo-4-fluorobenzene → (1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl)-(4-fluoro-phenyl)-methanone

https://huagongshe.com/reaction/1661323

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-4-fluorobenzeneHCID 9993—
Reactant1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazole-4-carboxylic acid methoxy-methyl-amideHCID 86634434—
Product(1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl)-(4-fluoro-phenyl)-methanoneHCID 67429480—

Reaction Steps

This compound is prepared by method C using compound 12j and 1-bromo-4-fluorobenzene

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030339B2
Source datasetuspto-grants-2011_10
ORD IDord-a981e5c1c7fb4860a375b913f3cab065
Source noteuspto-grants-2011_10