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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1661324Generated: October 30, 2026

1-Bromo-3-fluorobenzene → {1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl}-(3-fluoro-phenyl)-methanone

https://huagongshe.com/reaction/1661324

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-fluorobenzeneHCID 14082—
Reactant1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazole-4-carboxylic acid methoxy-methyl-amideHCID 86634434—
Product{1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl}-(3-fluoro-phenyl)-methanoneHCID 67429942—

Reaction Steps

This compound is prepared by method C using compound 12j and 1-bromo-3-fluorobenzene

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030339B2
Source datasetuspto-grants-2011_10
ORD IDord-0cba448ca61e48c08dd230c3e7a1850c
Source noteuspto-grants-2011_10