1-Methylimidazole → {1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl}-(1-methyl-1H-imidazol-2-yl)-methanone
Reaction equation
CON(C)[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([C:17]3[C:18]([F:24])=[N:19][CH:20]=[CH:21][C:22]=3[F:23])[CH:12]=2)[CH:10]=1)=[O:5].[CH3:26][N:27]1[CH:31]=[CH:30][N:29]=[CH:28]1>>[F:24][C:18]1[C:17]([C:13]2[CH:12]=[C:11]([N:9]3[CH:10]=[C:6]([C:4]([C:28]4[N:27]([CH3:26])[CH:31]=[CH:30][N:29]=4)=[O:5])[N:7]=[CH:8]3)[CH:16]=[CH:15][CH:14]=2)=[C:22]([F:23])[CH:21]=[CH:20][N:19]=1Participants
3
Procedure
This compound is prepared by method C using compound 12j and 1-methylimidazole
Workup
- customThis compound is prepared by method C
Sources & evidence
- ORD record
- ord-d1846ff64ef54c9ca714d29c387569c0
- Source dataset
- uspto-grants-2011_10
- Patent number
- US08030339B2
Reaction notes
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