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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1661388Generated: October 31, 2026

N-[2-(6-Amino-7-methoxy-2,3-dihydro-1H-inden-1-ylidene)ethyl]acetamide → N-[2-(6-amino-7-methoxy-2,3-dihydro-1H-inden-1-yl)ethyl]acetamide

https://huagongshe.com/reaction/1661388

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-[2-(6-Amino-7-methoxy-2,3-dihydro-1H-inden-1-ylidene)ethyl]acetamideHCID 67352334—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
ProductN-[2-(6-amino-7-methoxy-2,3-dihydro-1H-inden-1-yl)ethyl]acetamideHCID 5778126496.3%

Reaction Steps

N-[2-(6-Amino-7-methoxy-2,3-dihydro-1H-inden-1-ylidene)ethyl]acetamide (2.62 g, 10.7 mmol) was dissolved in methanol (50 mL), a 10% palladium-carbon powder (500 mg) was added, and the mixture was stirred at room temperature for 5 hr under a hydrogen atmosphere. The catalyst was filtered off using celite, and the filtrate was concentrated under reduced pressure to give the title compound (2.56 g, yield 96%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030337B2
Source datasetuspto-grants-2011_10
ORD IDord-377f8dedb94145f7a3e29a86719bf263
Source noteuspto-grants-2011_10