HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1R,2S)-1-[(1-isopropyl-1H-indazol-5-yl)oxy]-1-phenylpropan-2-amine → (1R,2S)-1-[(1-cyclopentyl-1H-indazol-5-yl)oxy]-1-phenylpropan-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1R,2S)-1-[(1-isopropyl-1H-indazol-5-yl)oxy]-1-phenylpropan-2-amine | HCID 59339639 | — |
| Reactant | 1-cyclopentyl-5-iodo-1H-indazole | HCID 59339790 | — |
| Product | (1R,2S)-1-[(1-cyclopentyl-1H-indazol-5-yl)oxy]-1-phenylpropan-2-amine | HCID 59339798 | — |
Reaction Steps
Prepared from 1-cyclopentyl-5-iodo-1H-indazole (37c, 158 mg, 500 μmol) as described for 30b. Yield 34 mg (20%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030340B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-03a27d785584476486897acc2780d2a9 |
| Source note | uspto-grants-2011_10 |