Ammonium formate → HCID 59786574, compound

Participants

Reaction Steps

Ammonium formate (1.13 g, 18 mmol) and palladium on charcoal (10%, 175 mg) is added to a solution of 1-(2-methoxypyridin-4-yl)-2-nitro-propan-1-ol (760 mg, 3.6 mmol) in 17.5 ml THF and 17.5 ml methanol. The reaction mixture is stirred overnight at room temperature, filtered through a path of cellites and concentrated. Yield 620 mg of a racemic mixture of two diastereomers, 95%.

Provenance & Evidence