HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(2-bromoethoxy)benzoate → 4-[2-(5-Chloro-3-methyl-2-pyridin-3-yl-indol-1-yl)-ethoxy]-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(2-bromoethoxy)benzoate | HCID 1898264 | — |
| Reactant | 5-chloro-3-methyl-2-pyridin-3-yl-1H-indole hydrochloride | HCID 44553962 | — |
| Product | 4-[2-(5-Chloro-3-methyl-2-pyridin-3-yl-indol-1-yl)-ethoxy]-benzoic acid methyl ester | HCID 58215690 | — |
Reaction Steps
4-(2-Bromo-ethoxy)-benzoic acid methyl ester (Example 61a) and 5-chloro-3-methyl-2-pyridin-3-yl-indol-1-yl (Example 2) are processed according to the method described in Example 59 to give 4-[2-(5-chloro-3-methyl-2-pyridin-3-yl-indol-1-yl)-ethoxy]-benzoic acid methyl ester. MS (ESI) m/z 421.01.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030334B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-ca088d3f95f14045ae5d122e36eece34 |
| Source note | uspto-grants-2011_10 |