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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1661646Generated: October 29, 2026

Acetonitrile → 2-(4-methoxy-pyridin-3-yl)-1H-indole-3,5-dicarbonitrile

https://huagongshe.com/reaction/1661646

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
Reactant2-(4-methoxy-pyridin-3-yl)-1H-indole-5-carbonitrileHCID 58215634—
Product2-(4-methoxy-pyridin-3-yl)-1H-indole-3,5-dicarbonitrileHCID 58215772—

Reaction Steps

2-(4-Methoxy-pyridin-3-yl)-1H-indole-5-carbonitrile (Example 128) is processed according to the method described in Example 140, using acetonitrile instead of dichloromethane, to give 2-(4-methoxy-pyridin-3-yl)-1H-indole-3,5-dicarbonitrile. MS (ESI) m/z 275.08 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030334B2
Source datasetuspto-grants-2011_10
ORD IDord-394337122d284975ae302a38eab3639f
Source noteuspto-grants-2011_10