1-BOC-6-methylindole-2-boronic acid → HCID 58215606, compound

HRID 1661729Notes

Reaction equation

HRID 1661729 reaction equation
Br[C:2]1[CH:3]=[C:4]([N:8]2[C:16](=[O:17])[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9]2=[O:18])[CH:5]=[N:6][CH:7]=1.C([N:26]1[C:34]2[C:29](=[CH:30][CH:31]=[C:32]([CH3:35])[CH:33]=2)[CH:28]=[C:27]1B(O)O)(OC(C)(C)C)=O>>[CH3:35][C:32]1[CH:33]=[C:34]2[C:29]([CH:28]=[C:27]([C:2]3[CH:3]=[C:4]([N:8]4[C:16](=[O:17])[C:15]5[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=5)[C:9]4=[O:18])[CH:5]=[N:6][CH:7]=3)[NH:26]2)=[CH:30][CH:31]=1

Participants

3

Reactant 2

HCID 35376741-BOC-6-methylindole-2-boronic acidHCID 58215795HCID 58215795, compound

Product 1

HCID 58215606HCID 58215606, compound

Procedure

2-(5-Bromo-pyridin-3-yl)-isoindole-1,3-dione and N-Boc-6-methyl-indoleboronic acid are processed according to the procedure described in Example 103 to give 2-[5-(6-methyl-1H-indol-2-yl)-pyridin-3-yl]-isoindole-1,3-dione. MS (ESI) m/z 354.1 (M+H)+

Sources & evidence

ORD record
ord-97b258e4b92843d4ab847104a5bf75d4
Source dataset
uspto-grants-2011_10
Patent number
US08030334B2

Reaction notes

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