Hydrazine → HCID 57654536, compound

Participants

Reaction Steps

(2-Chloro-quinolin-6-yl)-acetic acid methyl ester (0.160 g, 0.679 mmol), hydrazine (0.218 g, 6.79 mmol) and methanol (3 mL) were stirred at room temperature. The reaction was evaporated to give (2-chloro-quinolin-6-yl)-acetic acid hydrazide. This compound was not purified and was used directly in the next step. 1H NMR (400 MHz, DMSO-d6) δ 9.39 (m, 1H), 8.43 (d, 1H, J=9.2 Hz), 7.91 (m, 2H), 7.75 (m, 1H), 7.58 (m, 1H), 4.30 (bs, 2H), 3.57 (s, 2H).

Provenance & Evidence