Hydrochloric Acid → HCID 87119465, compound

Participants

Reaction Steps

To a solution of 6 (5.8 g, 17 mmol) in THF (30 mL) was added a mixture of HCl and THF (4 mL, 2 mL of c.HCl and 2 mL of THF. The reaction mixture was stirred for 4 h, concentrated to a wet solid and washed with 5% EtOAc/hexane. The product solidified (hygroscopic) under vacuum was used without further purification. 1H NMR (DMSO-d6): δ 1.28-1.37 (6H, m), 1.57-1.65 (4H, m), 2.65 (2H, t, J=7.3), 2.82 (4H, s), 4.02 (2H, t, J=6.3), 11.09 (3H, br s).

Provenance & Evidence