Nooglutyl → 2365144-97-2

Participants

Reaction Steps

Heat suspension of 2.68 g (0.01M) of N-(5-hydroxynicotinoyl)-L-glutamic acid in 50 ml of water up to 60-70° C. and add 0.68 g (0.012M) of calcium oxide in small portions. The sediment gradually dissolves. Heat the suspension for complete dissolution. Evaporate aquatic solution to 20 ml. Add resultant solution dropwise to 200 ml of ethanol. Mix formed precipitate for 0.5 hour and leave it for 12 hours at room temperature. Filter the precipitate, wash with alcohol and dry at 100° C. for constant weight (3 hours). Calcium N-(5-hydroxynicotinoyl)-L-glutamate (I) is obtained, recovery is 2.7 g (83%), [α]D20+11° (c 1, water).

Provenance & Evidence