HCID 57772056, compound → HCID 57772086, compound

HRID 1661924Notes

Reaction equation

HRID 1661924 reaction equation
[I:1][C:2]1[C:10]2[N:9]=[C:8]([C:11]3[CH:16]=[CH:15][C:14]([CH:17]([CH3:19])[CH3:18])=[CH:13][CH:12]=3)[N:7]([CH2:20][CH2:21][O:22][CH3:23])[C:6]=2[C:5]([O:24][CH3:25])=[CH:4][C:3]=1[CH:26]=[O:27].[CH3:28][O:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[Mg]Br>>[I:1][C:2]1[C:10]2[N:9]=[C:8]([C:11]3[CH:12]=[CH:13][C:14]([CH:17]([CH3:19])[CH3:18])=[CH:15][CH:16]=3)[N:7]([CH2:20][CH2:21][O:22][CH3:23])[C:6]=2[C:5]([O:24][CH3:25])=[CH:4][C:3]=1[CH:26]([C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][C:30]=1[O:29][CH3:28])[OH:27]

Participants

3

Reactant 2

HCID 57772056HCID 57772056, compoundHCID 178489560HCID 178489560, compound

Product 1

HCID 57772086HCID 57772086, compound

Procedure

The title compound is prepared from 4-iodo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole-5-carbaldehyde and 2-methoxyphenyl-magnesium bromide as described in example 35.

Sources & evidence

ORD record
ord-ea916468fbb64cc787984688468696a5
Source dataset
uspto-grants-2011_10
Patent number
US08030497B2

Reaction notes

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