Ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-carbamic acid 4-chloro-benzyl ester → (2'-{[(4-Chloro-benzyloxycarbonyl)-ethyl-amino]-methyl}-5,4'-bis-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester
Reaction equation
[CH3:35][O:36][C:37]([CH2:38][c:39]1[cH:40][c:41]([O:49][S:50]([C:51]([F:52])([F:53])[F:54])(=[O:55])=[O:56])[cH:42][c:43]([C:45]([F:46])([F:47])[F:48])[cH:44]1)=[O:57].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][C:8]([N:9]([CH2:10][c:11]2[c:12]([B:21]3[O:22][C:23]([CH3:24])([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29]3)[cH:13][cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[CH2:30][CH3:31])=[O:32])[cH:33][cH:34]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][C:8]([N:9]([CH2:10][c:11]2[c:12](-[c:41]3[cH:40][c:39]([CH2:38][C:37]([O:36][CH3:35])=[O:57])[cH:44][c:43]([C:45]([F:46])([F:47])[F:48])[cH:42]3)[cH:13][cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[CH2:30][CH3:31])=[O:32])[cH:33][cH:34]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8c416f230fd84245ae66d21a5cff27ef
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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