4-Bromo-2-methylpyridine → HCID 58579493, compound

HRID 1662219Notes

Reaction equation

HRID 1662219 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([C:8]([C:16]2[CH:21]=[C:20]([Cl:22])[CH:19]=[C:18]([F:23])[C:17]=2[C:24]#[N:25])=[N:9]S(C(C)(C)C)=O)[CH:5]=[CH:6][CH:7]=1.Br[C:27]1[CH:32]=[CH:31][N:30]=[C:29]([CH3:33])[CH:28]=1>>[Br:1][C:2]1[CH:3]=[C:4]([C:8]2([C:27]3[CH:32]=[CH:31][N:30]=[C:29]([CH3:33])[CH:28]=3)[C:16]3[C:17](=[C:18]([F:23])[CH:19]=[C:20]([Cl:22])[CH:21]=3)[C:24]([NH2:25])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 27628354-Bromo-2-methylpyridineHCID 76821605HCID 76821605, compound

Product 1

HCID 58579493HCID 58579493, compoundYield 83%

Procedure

The title compound was synthesized as described for Example 11i in 83% yield, starting from N-((3-bromophenyl)(5-chloro-2-cyano-3-fluorophenyl)methylene)-2-methylpropane-2-sulfinamide (2 g, 4.53 mmol) and 4-bromo-2-methylpyridine (0.935 g, 5.43 mmol)

Sources & evidence

ORD record
ord-2b31596ee783438494334b00b599a367
Source dataset
uspto-grants-2011_10
Patent number
US08030500B2

Reaction notes

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