Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1662230Generated: October 26, 2026

(Pyrimidin-5-yl)boronic acid → HCID 46205964, compound

https://huagongshe.com/reaction/1662230

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Pyrimidin-5-yl)boronic acidHCID 2795193—
Reactant1-(5-Bromo-2-fluorophenyl)-4-fluoro-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amineHCID 58579538—
ProductHCID 46205964HCID 4620596458%

Reaction Steps

The title compound was synthesized as described for Example 1 in 58% yield, starting from 1-(5-bromo-2-fluorophenyl)-4-fluoro-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amine (59.0 mg, 0.13 mmol), pyrimidin-5-ylboronic acid (17.17 mg, 0.14 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030500B2
Source datasetuspto-grants-2011_10
ORD IDord-c459b26e669c4402bdf82046b4a85871
Source noteuspto-grants-2011_10