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HRID1662231

反应详情

EQUATION

反应方程式

HRID 1662231 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2cncc(C#N)c2)OC1(C)C
HCID16414216

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile

C12H15BN2O2

结构：NC1=NC(c2ccnc(C(F)(F)F)c2)(c2cc(Br)ccc2F)c2cccc(F)c21
HCID58579538

未命名化合物

PRODUCTS

生成物

1
结构：N#Cc1cncc(-c2ccc(F)c(C3(c4ccnc(C(F)(F)F)c4)N=C(N)c4c(F)cccc43)c2)c1
HCID46205642

未命名化合物

收率 65%

PROCEDURE

实验过程

The title compound was synthesized as described for Example 1 in 65% yield, starting from 1-(5-bromo-2-fluorophenyl)-4-fluoro-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amine (60.0 mg, 0.13 mmol) and 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile (32.4 mg, 0.14 mmol).