HCID 131729219, compound → HCID 11515217, compound

Participants

Reaction Steps

To 1.33 g (2.40 mmol) of Compound 5, ammonia-saturated methanol (120 ml) was added at 0° C. The solution was stirred at room temperature for 2 hours. After the reaction, the solvent was distilled off and the residue was purified by flash silica gel chromatography using methylene chloride:ethanol (97:3 to 93:7) as an elution solvent to give 717 mg of Compound 6 in a yield of 94%.

Provenance & Evidence