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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1662295Generated: October 29, 2026

1-(beta-D-Ribofuranosyl)pyrrole-2-carbaldehyde → 4-Propynyl-1-(beta-D-ribofuranosyl)pyrrole-2-carbaldehyde

https://huagongshe.com/reaction/1662295

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(beta-D-Ribofuranosyl)pyrrole-2-carbaldehydeHCID 44433306—
Reactant4-Propynylpyrrole-2-carbaldehydeHCID 45079201—
Product4-Propynyl-1-(beta-D-ribofuranosyl)pyrrole-2-carbaldehydeHCID 86639014—

Reaction Steps

4-Propynyl-1-(β-D-ribofuranosyl)pyrrole-2-carbaldehyde (Compound 18) was synthesized in the same manner as used for Compound 17, starting with 4-propynyl-2-pyrrolecarbaldehyde (Compound 16) (Non-patent Document 40) (266 mg, 2.0 mmol). After purification by RP-HPLC, Compound 18 was obtained (39 mg, 7%, 2 steps).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030478B2
Source datasetuspto-grants-2011_10
ORD IDord-95b5060e29264edd80ee125312182c2c
Source noteuspto-grants-2011_10