反应详情

Compound 13 was synthesized from methyl 3-(3-hydroxyphenyl)propanoate (available from Aagile Labs Division of Tyger Scientific) and 5.4 by a method analogous to the method used to prepare compound 7. ESI (neg.) m/e: 451.1 (M−H)+. 1H NMR (400 MHz, CDCl3) δ ppm 7.22-7.32 (2H, m), 7.01-7.09 (3H, m), 6.82-6.91 (5H, m), 5.08 (2H, s), 4.00 (2H, t, J=6.5 Hz), 3.81 (3H, s), 2.97 (2H, t, J=7.8 Hz), 2.71 (2H, t, J=7.8 Hz), 1.64-1.72 (2H, m), 1.34-1.43 (2H, m), 0.90 (3H, t, J=7.3 Hz).