5-(1-(3-Hydroxyphenyl)-2-methyl-2-propenyl)-2,2-dimethyl-1,3-dioxane-4,6-dione → 3-(3-Hydroxyphenyl)-4-methyl-4-pentenoic acid

HRID 1662360Notes

Reaction equation

HRID 1662360 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]([CH:12]2C(=O)OC(C)(C)[O:14][C:13]2=[O:21])[C:9]([CH3:11])=[CH2:10])[CH:5]=[CH:6][CH:7]=1.OC1C=C(C(CC=C)CC(O)=O)C=CC=1>>[OH:1][C:2]1[CH:3]=[C:4]([CH:8]([C:9]([CH3:11])=[CH2:10])[CH2:12][C:13]([OH:21])=[O:14])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 577057455-(1-(3-Hydroxyphenyl)-2-methyl-2-propenyl)-2,2-dimethyl-1,3-dioxane-4,6-dioneHCID 577065823-(3-Hydroxyphenyl)-5-hexenoic acid

Product 1

HCID 577068433-(3-Hydroxyphenyl)-4-methyl-4-pentenoic acidYield 101.8%

Procedure

Compound 48.1 (0.88 g, 3.0 mmol) was hydrolyzed according to the method described for preparation of 43.2 to afford 48.2 (0.63 g).

Sources & evidence

ORD record
ord-4d5355f95a204157b9cd1b25632367e5
Source dataset
uspto-grants-2011_10
Patent number
US08030354B2

Reaction notes

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