3-(3-Hydroxyphenyl)-4-methyl-4-pentenoic acid → Methyl 3-(3-hydroxyphenyl)-4-methyl-4-pentenoate

HRID 1662361Notes

Reaction equation

HRID 1662361 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]([C:13]([CH3:15])=[CH2:14])[CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[CH:6][CH:7]=1.O[C:17]1C=C(C(CC=C)CC(OC)=O)C=CC=1>>[OH:1][C:2]1[CH:3]=[C:4]([CH:8]([C:13]([CH3:15])=[CH2:14])[CH2:9][C:10]([O:12][CH3:17])=[O:11])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 577068433-(3-Hydroxyphenyl)-4-methyl-4-pentenoic acidHCID 57707209Methyl 3-(3-hydroxyphenyl)-5-hexenoate

Product 1

HCID 57706779Methyl 3-(3-hydroxyphenyl)-4-methyl-4-pentenoateYield 83%

Procedure

Compound 48.2 (0.63 g, 3.1 mmol) was esterified according to the method described for preparation of 43.3 to afford 48.3 (0.56 g, 83%) as a colorless oil.

Sources & evidence

ORD record
ord-e6ddc4fe5ca84bcdb29af10b272d957a
Source dataset
uspto-grants-2011_10
Patent number
US08030354B2

Reaction notes

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