HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57706290, compound → HCID 22926843, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57706290 | HCID 57706290 | — |
| Reactant | Benzenepropanoic acid, 3-hydroxy-α-methyl-, ethyl ester, (αR)- | HCID 57707095 | — |
| Reactant | HCID 67428994 | HCID 67428994 | — |
| Reactant | HCID 67430489 | HCID 67430489 | — |
| Product | HCID 22926843 | HCID 22926843 | — |
Reaction Steps
Methyl (2R)-3-(3-hydroxyphenyl)-2-methylpropanoate (62) and methyl (2S)-3-(3-hydroxyphenyl)-2-methylpropanoate (63). Racemic ethyl 3-(3-hydroxyphenyl)-2-methylpropanoate 62.C (0.40 g) was separated by ChiralPak OJ-H column, eluted with 10% isopropanol in hexane to give the separated enantiomers; (R)-ethyl 3-(3-hydroxyphenyl)-2-methylpropanoate and (S)-ethyl 3-(3-hydroxyphenyl)-2-methylpropanoate 62 and 63. MS ESI (pos.) m/e: 209.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030354B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-c9f5aa1d0f784c08a58d022781768ff4 |
| Source note | uspto-grants-2011_10 |