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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1662555Generated: October 30, 2026

2,2-Dimethyl-1,3-dioxane-4,6-dione → 2,2-Dimethyl-5-(1-methylethylidene)-1,3-dioxane-4,6-dione

https://huagongshe.com/reaction/1662555

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 16249—
Reactant(3S)-3-(3-(((2-(butyloxy)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methyl)oxy)phenyl)butanoic acidHCID 57705600—
Product2,2-Dimethyl-5-(1-methylethylidene)-1,3-dioxane-4,6-dioneHCID 75218—

Reaction Steps

The 2,2-dimethyl-5-(propan-2-ylidene)-1,3-dioxane-4,6-dione (85.B) was prepared from 2,2-dimethyl-1,3-dioxane-4,6-dione 85.A (commercially available from Aldrich) via the same procedure described in Vogt, P. F.; et. al.; Synthetic Communications; 2001, (5); pp. 679-684.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030354B2
Source datasetuspto-grants-2011_10
ORD IDord-360fe80e123e419ab6cbcd1ae0848ceb
Source noteuspto-grants-2011_10