HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl (trimethylsilyl)acetate → Methyl 3-(3-(tert-butyldimethylsilyloxy)-2,5-difluorophenyl)pent-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl (trimethylsilyl)acetate | HCID 76210 | — |
| Reactant | 1-(3-(tert-Butyldimethylsilyloxy)-2,5-difluorophenyl)propan-1-one | HCID 57706378 | — |
| Product | Methyl 3-(3-(tert-butyldimethylsilyloxy)-2,5-difluorophenyl)pent-2-enoate | HCID 67432312 | — |
Reaction Steps
Compound 90.E (mixture of geometric isomers) was prepared from 90.D and methyl (trimethylsilyl)acetate (available from Aldrich) according to the analogous method described in Example 84.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030354B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-06ccf384821b488f91ba28cb88a127c9 |
| Source note | uspto-grants-2011_10 |