HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Cyclohexylidene-2,2-dimethyl-1,3-dioxane-4,6-dione → 5-(1-(3-Methoxyphenyl)cyclohexyl)-2,2-dimethyl-1,3-dioxane-4,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Cyclohexylidene-2,2-dimethyl-1,3-dioxane-4,6-dione | HCID 597201 | — |
| Reactant | 3-(3-(((2-Methyl-3'-(methyloxy)-1,1'-biphenyl-4-yl)methyl)oxy)phenyl)propanoic acid | HCID 25261298 | — |
| Reactant | HCID 178490745 | HCID 178490745 | — |
| Product | 5-(1-(3-Methoxyphenyl)cyclohexyl)-2,2-dimethyl-1,3-dioxane-4,6-dione | HCID 11336520 | — |
Reaction Steps
5-(2-(3-Methoxyphenyl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione (105.B) was prepared from 105.A and (3-methoxyphenyl)magnesium bromide (1.0 M in THF solution from Aldrich) using a procedure described in Huang, X.; et. al.; Tetrahedron Letters; 1982, (1); pp. 75-76. MS ESI (neg.) m/e: 331.1 (M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030354B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-ee23b7a96bd64ac8817f82c6608ef90b |
| Source note | uspto-grants-2011_10 |