HuagongsheHuagongshe Chemistry Print Report · For research reference only
o-Bromocumene → 5-chloro-3-hydroxy-3-(2-isopropylphenyl)-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | o-Bromocumene | HCID 23475 | — |
| Reactant | 5-chloro-1H-indole-2,3-dione | HCID 87203 | — |
| Product | 5-chloro-3-hydroxy-3-(2-isopropylphenyl)-1,3-dihydro-2H-indol-2-one | HCID 23120709 | 98.3% |
Reaction Steps
With 8.2 g of 1-bromo-2-isopropyl benzene and 3.0 g of 5-chloroisatin as starting materials, 4.9 g of the title compound (pale yellow amorphous) was obtained by a similar method to Step 21-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-fa1ccbd87f584dc99317e5a700af163c |
| Source note | uspto-grants-2011_10 |