HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 3-Benzyl-5-chloro-1,3-dihydro-3-hydroxyindol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 5-chloro-1H-indole-2,3-dione | HCID 87203 | — |
| Product | 3-Benzyl-5-chloro-1,3-dihydro-3-hydroxyindol-2-one | HCID 19076619 | 37.3% |
Reaction Steps
With 5.00 g of benzyl bromide and 1.50 g of 5-chloroisatin as starting material, 844 mg of the title compound (white solid) was obtained by a similar method to Step 21-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-776300aab1d9425bb87343a6160d0929 |
| Source note | uspto-grants-2011_10 |