3-Amino-1-methanesulfonylpyrrolidine → 6-Chloro-N-[1-(methylsulfonyl)-3-pyrrolidinyl]-2-{4-[2-(4-morpholinyl)ethoxy]phenyl}-1H-imidazo[4,5-b]pyridin-7-amine

HRID 166262Notes

Reaction equation

HRID 166262 reaction equation
[CH3:27][S:28](=[O:29])(=[O:30])[N:31]1[CH2:32][CH:33]([NH2:36])[CH2:34][CH2:35]1.[Cl:1][c:2]1[c:3]([Cl:26])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][c:9](-[c:11]1[cH:12][cH:13][c:14]([O:17][CH2:18][CH2:19][N:20]3[CH2:21][CH2:22][O:23][CH2:24][CH2:25]3)[cH:15][cH:16]1)[n:10]2>>[Cl:1][c:2]1[c:3]([NH:36][CH:33]2[CH2:32][N:31]([S:28]([CH3:27])(=[O:29])=[O:30])[CH2:35][CH2:34]2)[c:4]2[c:5]([n:6][cH:7]1)[n:8][c:9](-[c:11]1[cH:12][cH:13][c:14]([O:17][CH2:18][CH2:19][N:20]3[CH2:21][CH2:22][O:23][CH2:24][CH2:25]3)[cH:15][cH:16]1)[nH:10]2

Participants

3

Reactant 2

HCID 533932533-Amino-1-methanesulfonylpyrrolidineHCID 178478272HCID 178478272, compound

Product 1

HCID 117564546-Chloro-N-[1-(methylsulfonyl)-3-pyrrolidinyl]-2-{4-[2-(4-morpholinyl)ethoxy]phenyl}-1H-imidazo[4,5-b]pyridin-7-amine

Sources & evidence

ORD record
ord-b30a9269b7c2438c8536439ffe79fb08
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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