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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1662650Generated: October 29, 2026

3,5-Dichloro-3-(2-methoxyphenyl)indolin-2-one → 2-{[5-chloro-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]amino}-N,N-dimethylacetamide

https://huagongshe.com/reaction/1662650

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Dichloro-3-(2-methoxyphenyl)indolin-2-oneHCID 21905913—
ReactantHCID 21936803HCID 21936803—
Product2-{[5-chloro-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]amino}-N,N-dimethylacetamideHCID 67428954—

Reaction Steps

With 2.01 g of 3,5-dichloro-3-(2-methoxyphenyl)-1,3-dihydro-2H-indol-2-one and the compound obtained in Step 62-2 (7.81 mmol, crude form) as starting material, 1.91 g of the title compound (colorless powder) was obtained by a similar method to Step 4-2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030499B2
Source datasetuspto-grants-2011_10
ORD IDord-b2047395f7704c3c95b2d22ad0824759
Source noteuspto-grants-2011_10