HCID 67429904, compound → HCID 59867952, compound

HRID 1662656Notes

Reaction equation

HRID 1662656 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2([NH:20][C@@H:21]([CH2:27][C:28]([NH2:30])=[O:29])[C:22]([N:24]([CH3:26])[CH3:25])=[O:23])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18][CH3:19].[CH3:31][O:32][C:33]1[CH:38]=[CH:37][C:36]([S:39](Cl)(=[O:41])=[O:40])=[C:35]([O:43][C:44]([F:47])([F:46])[F:45])[CH:34]=1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:39]([C:36]1[CH:37]=[CH:38][C:33]([O:32][CH3:31])=[CH:34][C:35]=1[O:43][C:44]([F:45])([F:46])[F:47])(=[O:41])=[O:40])[C:6](=[O:11])[C:5]2([NH:20][C@@H:21]([CH2:27][C:28]([NH2:30])=[O:29])[C:22]([N:24]([CH3:25])[CH3:26])=[O:23])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18][CH3:19]

Participants

3

Reactant 2

HCID 67429904HCID 67429904, compoundHCID 866256844-Methoxy-2-(trifluoromethoxy)benzene sulfonyl chloride

Product 1

HCID 59867952HCID 59867952, compoundYield 55.9%

Procedure

With 296 mg of the compound obtained in Step 67-3 and 204 mg of 4-methoxy-2-(trifluoromethoxy)benzene sulfonyl chloride as starting materials, 263 mg of the title compound (colorless amorphous) was obtained by a similar method to Example 2.

Sources & evidence

ORD record
ord-00128da8df6b4ceb83a9829c0beb1a69
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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