HCID 15130877, compound → HCID 14963845, compound

HRID 1662671Notes

Reaction equation

HRID 1662671 reaction equation
C(OC(=O)[NH:10][C@H:11]([C:15]([N:17]([CH3:19])[CH3:18])=[O:16])[CH:12]([CH3:14])[CH3:13])C1C=CC=CC=1>CCO.[C].[Pd]>[NH2:10][C@@H:11]([CH:12]([CH3:14])[CH3:13])[C:15]([N:17]([CH3:19])[CH3:18])=[O:16]

Participants

4

Reactant 1

HCID 15130877HCID 15130877, compound

Product 1

HCID 14963845HCID 14963845, compoundYield 99.3%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

A suspension of 2.04 g of the compound obtained in Step 82-1 and 0.3 g of 10% palladium-carbon in EtOH (20 ml) was stirred at room temperature for two hours under hydrogen atmosphere. The insoluble matter was separated by filtration and the filtrate was concentrated to obtain 1.05 g of the title compound (pale yellow oil).

Workup

  1. customThe insoluble matter was separated by filtration
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-df15f0fa7e2941bebbadb441f74acd5d
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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