Methanol → HCID 59753527, compound

Participants

Reaction Steps

To a solution of 1.47 g of the compound obtained in Step 84-1 in a mixed solution of MeOH and THF (25 ml 4:1; v/v) was added a solution of 2 mol/L dimethylamine MeOH (5.8 ml) and the reaction solution was stirred at room temperature for 24 hours. The reaction solution was concentrated under vacuum and the obtained residue was purified by column chromatography (silicagel 60; mobile phase: CHCl3/MeOH=9/1 to 5/1; v/v) to obtain 0.60 g of the title compound (brown oil).

Provenance & Evidence