2-Bromo-4-chloroanisole → HCID 23120690, compound

HRID 1662688Notes

Reaction equation

HRID 1662688 reaction equation
Br[C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[O:9][CH3:10].[Cl:11][C:12]1[C:13]([CH3:23])=[C:14]2[C:18](=[CH:19][CH:20]=1)[NH:17][C:16](=[O:21])[C:15]2=[O:22]>>[Cl:11][C:12]1[C:13]([CH3:23])=[C:14]2[C:18](=[CH:19][CH:20]=1)[NH:17][C:16](=[O:21])[C:15]2([C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[O:9][CH3:10])[OH:22]

Participants

3

Reactant 2

HCID 5219352-Bromo-4-chloroanisoleHCID 23120703HCID 23120703, compound

Product 1

HCID 23120690HCID 23120690, compoundYield 71.7%

Procedure

With 4.75 g of 2-bromo-4-chloro-1-methoxy benzene and 1.96 g of 5-chloro-4-methyl-1H-indol-2,3-dione as starting materials, 2.43 g of the title compound (yellow solid) was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record
ord-15ea6eda608b4fb397b269252675a36d
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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