HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-methylanisole → 4,5-dichloro-3-hydroxy-3-(2-methoxy-5-methylphenyl)-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-methylanisole | HCID 89143 | — |
| Reactant | 4,5-Dichloro-1H-indole-2,3-dione | HCID 5139980 | — |
| Product | 4,5-dichloro-3-hydroxy-3-(2-methoxy-5-methylphenyl)-1,3-dihydro-2H-indol-2-one | HCID 23120706 | 52.4% |
Reaction Steps
With 3.02 g of 2-bromo-1-methoxy-4-methyl benzene and 1.50 g of 4,5-dichloroisatin as starting materials, 1.23 g of the title compound (yellow solid) was obtained by a similar method to Step 21-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-0dc6a4f4d3a04484ac6f759c8da195ae |
| Source note | uspto-grants-2011_10 |