HCID 67428714, compound → HCID 11952159, compound

Participants

Reaction Steps

With 150 mg of (4R)-1-[5-chloro-3-(2,4-dimethoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-L-prolinamide (levorotatory compound), which is the compound described in Preparation 3.39 of brochure Publication No. WO01/055130 and 110 mg of 4-methoxy-2-(trifluoromethoxy)benzene sulfonyl chloride as starting materials, 91 mg of the title compound (yellow amorphous) was obtained by a similar method to Example 2.

Provenance & Evidence