HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-chloro-1H-indole-2,3-dione → 5-chloro-3-hydroxy-3-(2-methoxy-5-methylphenyl)-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-chloro-1H-indole-2,3-dione | HCID 87203 | — |
| Reactant | 2-Bromo-4-methylanisole | HCID 89143 | — |
| Product | 5-chloro-3-hydroxy-3-(2-methoxy-5-methylphenyl)-1,3-dihydro-2H-indol-2-one | HCID 67429477 | 90.8% |
Reaction Steps
With 4.36 g of 3-bromo-4-methoxy toluene and 2.81 g of 5-chloroisatin as starting materials, 4.27 g of the title compound (light brown solid) was obtained by a similar method to Step 21-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-3cc28030a37a421385a3baaf3738b93a |
| Source note | uspto-grants-2011_10 |