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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1662692Generated: October 26, 2026

2-Bromostyrene → 5-chloro-3-hydroxy-3-(2-vinylphenyl)-1,3-dihydro-2H-indol-2-one

https://huagongshe.com/reaction/1662692

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromostyreneHCID 16264—
Reactant5-chloro-1H-indole-2,3-dioneHCID 87203—
Product5-chloro-3-hydroxy-3-(2-vinylphenyl)-1,3-dihydro-2H-indol-2-oneHCID 6742923176.9%

Reaction Steps

With 10.0 g of 1-bromo-2-vinyl benzene and 4.72 g of 5-chloroisatin as starting materials, 5.71 g of the title compound (light brown solid) was obtained by a similar method to Step 21-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030499B2
Source datasetuspto-grants-2011_10
ORD IDord-5f59e55a8356437aa568006ef54de2f4
Source noteuspto-grants-2011_10