5-Bromoisatin → HCID 67430130, compound

HRID 1662693Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH3:8].[Br:9][C:10]1[CH:11]=[C:12]2[C:16](=[CH:17][CH:18]=1)[NH:15][C:14](=[O:19])[C:13]2=[O:20]>>[Br:9][C:10]1[CH:11]=[C:12]2[C:16](=[CH:17][CH:18]=1)[NH:15][C:14](=[O:19])[C:13]2([OH:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH3:8]

Participants

Reactant 2

HCID 68895-Bromoisatin

HCID 72362-Bromotoluene

Product 1

HCID 67430130HCID 67430130, compoundYield 50.1%

Procedure

With 9.58 g of 1-bromo-2-methyl benzene and 4.52 g of 5-bromoisatin as starting materials, 3.19 g of the title compound (brown solid) was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record: ord-1bd9a4364d3942ba8589ba4eb1fcd630
Source dataset: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08030499B2

Reaction notes

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