2-Bromotoluene → HCID 67431076, compound

HRID 1662694Notes

Reaction equation

[I:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=[O:12].Br[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH3:20]>>[OH:12][C:5]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[CH3:20])[C:4]2[C:8](=[CH:9][CH:10]=[C:2]([I:1])[CH:3]=2)[NH:7][C:6]1=[O:11]

Participants

Reactant 2

HCID 72362-Bromotoluene

HCID 886955-Iodoisatin

Product 1

HCID 67431076HCID 67431076, compound

Procedure

With 5.46 g of 5-iodoisatin and 1-bromo-2-methyl benzene as starting materials, 5.87 g of the title compound (brown solid) was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record: ord-980bd1b6f67847a3b6343b4e439e1ec0
Source dataset: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08030499B2

Reaction notes

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