5-Methylisatin → HCID 67427852, compound

HRID 1662695Notes

Reaction equation

HRID 1662695 reaction equation
Br[C:2]1[C:10]2[O:9][CH2:8][O:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH3:11][C:12]1[CH:13]=[C:14]2[C:18](=[CH:19][CH:20]=1)[NH:17][C:16](=[O:21])[C:15]2=[O:22]>>[O:7]1[C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([C:15]3([OH:22])[C:14]4[C:18](=[CH:19][CH:20]=[C:12]([CH3:11])[CH:13]=4)[NH:17][C:16]3=[O:21])[C:10]=2[O:9][CH2:8]1

Participants

3

Reactant 2

HCID 118405-MethylisatinHCID 27761894-Bromo-1,3-benzodioxole

Product 1

HCID 67427852HCID 67427852, compoundYield 68.9%

Procedure

With 7.80 g of 4-bromo-1,3-benzodioxol and 1.61 g of 5-methyl isatin as starting materials, 1.95 g of the title compound (brown solid) was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record
ord-e9201895ce404a8db9ef66cabb0da0a2
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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