HCID 23521553, compound → HCID 67430202, compound

HRID 1662697Notes

Reaction equation

HRID 1662697 reaction equation
[CH3:1][N:2]([CH3:18])[C:3]([CH:5]1[NH:10][CH2:9][CH2:8][N:7]([C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])[CH2:6]1)=[O:4].Cl[C:20]1([C:31]2[CH:36]=[C:35]([CH3:37])[CH:34]=[CH:33][C:32]=2[O:38][CH3:39])[C:28]2[C:23](=[CH:24][CH:25]=[C:26]([Cl:29])[CH:27]=2)[NH:22][C:21]1=[O:30]>>[Cl:29][C:26]1[CH:27]=[C:28]2[C:23](=[CH:24][CH:25]=1)[NH:22][C:21](=[O:30])[C:20]2([N:10]1[CH2:9][CH2:8][N:7]([C:11]([O:13][C:14]([CH3:15])([CH3:17])[CH3:16])=[O:12])[CH2:6][CH:5]1[C:3]([N:2]([CH3:18])[CH3:1])=[O:4])[C:31]1[CH:36]=[C:35]([CH3:37])[CH:34]=[CH:33][C:32]=1[O:38][CH3:39]

Participants

3

Reactant 2

HCID 23521553HCID 23521553, compoundHCID 67428438HCID 67428438, compound

Product 1

HCID 67430202HCID 67430202, compoundYield 43.5%

Procedure

With 2.43 g of the compound obtained in Step 109-3 and 2.43 g of the compound obtained in Step 109-4 as starting materials, 1.78 g of the title compound was obtained by a similar method to Step 4-2.

Sources & evidence

ORD record
ord-c0c3e16c525b4fa190677323b3de6037
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

Loading…