5-Bromoisatin → HCID 67429507, compound

HRID 1662707Notes

Reaction equation

HRID 1662707 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH3:10])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[Br:11][C:12]1[CH:13]=[C:14]2[C:18](=[CH:19][CH:20]=1)[NH:17][C:16](=[O:21])[C:15]2=[O:22]>>[Br:11][C:12]1[CH:13]=[C:14]2[C:18](=[CH:19][CH:20]=1)[NH:17][C:16](=[O:21])[C:15]2([OH:22])[C:2]1[CH:3]=[C:4]([CH3:10])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9]

Participants

3

Reactant 2

HCID 68895-BromoisatinHCID 891432-Bromo-4-methylanisole

Product 1

HCID 67429507HCID 67429507, compoundYield 90.2%

Procedure

With 56.3 g of 3-bromo-4-methoxy toluene and 45.2 g of 5-bromoisatin as starting materials, 62.8 g of the title compound was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record
ord-74787b505e1a470fa140ff8e68c1249f
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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