HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-methylanisole → 3-hydroxy-3-(2-methoxy-5-methylphenyl)-5-nitro-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-methylanisole | HCID 89143 | — |
| Reactant | 5-Nitroisatin | HCID 4669250 | — |
| Product | 3-hydroxy-3-(2-methoxy-5-methylphenyl)-5-nitro-1,3-dihydro-2H-indol-2-one | HCID 67429938 | 95.8% |
Reaction Steps
With 10.0 g of 2-bromo-4-methyl anisole and 6.00 g of 5-nitroisatin as starting materials, 9.40 g of the title compound (brown solid) was obtained by a similar method to Step 21-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-ef38210aac5f45438c2f6f11af7b4789 |
| Source note | uspto-grants-2011_10 |